Kenneth Walsh Selected Research

Cardiomegaly (Heart Hypertrophy)

1/2018	CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease.
12/2010	T-cadherin is critical for adiponectin-mediated cardioprotection in mice.
3/2010	Modulation of angiotensin II-mediated cardiac remodeling by the MEF2A target gene Xirp2.
12/2009	Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction.
11/2009	Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy.
11/2007	Potential of adiponectin as a cardioprotective agent.
6/2007	Adiponectin protects against the development of systolic dysfunction following myocardial infarction.
10/2006	Microarray analysis of Akt1 activation in transgenic mouse hearts reveals transcript expression profiles associated with compensatory hypertrophy and failure.
5/2006	Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload.
12/2004	Adiponectin-mediated modulation of hypertrophic signals in the heart.

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Kenneth Walsh Research Topics

Disease

37	Obesity 11/2022 - 12/2003
25	Inflammation (Inflammations) 01/2021 - 01/2002
20	Ischemia 01/2018 - 07/2004
16	Hypertrophy 01/2019 - 05/2002
16	Insulin Resistance 12/2017 - 11/2004
15	Cardiovascular Diseases (Cardiovascular Disease) 07/2022 - 04/2007
14	Heart Failure 01/2022 - 10/2002
14	Reperfusion Injury 02/2016 - 04/2003
13	Myocardial Infarction 01/2020 - 10/2005
12	Atherosclerosis 01/2021 - 12/2003
11	Neoplasms (Cancer) 01/2023 - 01/2002
10	Fibrosis (Cirrhosis) 10/2018 - 05/2006
10	Cardiomegaly (Heart Hypertrophy) 01/2018 - 12/2004
10	Hypoxia (Hypoxemia) 07/2013 - 08/2003
7	Hypoadiponectinemia 04/2013 - 12/2003
6	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 12/2003
6	Myocardial Ischemia (Ischemic Heart Diseases) 05/2016 - 10/2005
6	Hypertension (High Blood Pressure) 09/2010 - 06/2006
6	Hyperplasia 02/2007 - 08/2002
5	Type 2 Diabetes Mellitus (MODY) 03/2016 - 12/2003
5	Infarction (Infarctions) 01/2016 - 10/2005
5	Alzheimer Disease (Alzheimer's Disease) 07/2014 - 02/2004
4	Cardiotoxicity 01/2021 - 10/2002
4	Diabetes Mellitus 03/2016 - 01/2009
4	Autoimmune Diseases (Autoimmune Disease) 01/2009 - 01/2003
3	Glucose Intolerance 07/2022 - 07/2010
3	Cardiomyopathies (Cardiomyopathy) 01/2021 - 03/2004
3	Heart Diseases (Heart Disease) 01/2016 - 11/2007
3	Muscular Dystrophies (Muscular Dystrophy) 01/2016 - 01/2009
3	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 12/2015 - 01/2010
3	Inclusion Body Myositis 07/2014 - 10/2006
3	Vascular System Injuries 07/2014 - 08/2002
3	Starvation 01/2013 - 04/2004
3	Atrophy 05/2012 - 04/2004
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2012 - 06/2006
3	Metabolic Diseases (Metabolic Disease) 02/2011 - 07/2008
3	Vascular Remodeling 09/2010 - 12/2003
3	Pathologic Neovascularization 01/2010 - 08/2006
3	Vascular Diseases (Vascular Disease) 01/2009 - 12/2003
2	Microvascular Rarefaction 11/2022 - 05/2014
2	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2022 - 01/2022
2	Left Ventricular Dysfunction 10/2018 - 12/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 12/2015 - 05/2003
2	Carcinogenesis 10/2014 - 11/2002
2	Myositis (Idiopathic Inflammatory Myopathies) 07/2014 - 01/2014

Drug/Important Bio-Agent (IBA)

46	AdiponectinIBA 12/2015 - 12/2003
17	Proteins (Proteins, Gene)FDA Link 01/2024 - 05/2002
16	AdipokinesIBA 01/2022 - 12/2003
14	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2022 - 01/2002
13	Insulin (Novolin)FDA Link 10/2018 - 07/2002
11	CytokinesIBA 02/2020 - 01/2003
9	Glucose (Dextrose)FDA LinkGeneric 04/2015 - 11/2004
9	Hormones (Hormone)IBA 04/2013 - 04/2007
7	LipidsIBA 07/2015 - 11/2004
6	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 05/2003
6	FollistatinIBA 01/2016 - 03/2011
6	AMP-Activated Protein KinasesIBA 12/2015 - 08/2003
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2015 - 11/2003
5	Blood Proteins (Serum Proteins)IBA 01/2022 - 08/2006
5	Angiotensin IIIBA 01/2020 - 05/2002
5	Sirolimus (Rapamycin)FDA Link 12/2009 - 08/2006
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 10/2002
4	Interleukin-6 (Interleukin 6)IBA 01/2021 - 12/2003
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 07/2002
4	LigandsIBA 01/2019 - 11/2003
4	Protein Kinases (Protein Kinase)IBA 07/2013 - 08/2003
4	Messenger RNA (mRNA)IBA 05/2012 - 06/2006
4	Amyloid beta-PeptidesIBA 12/2008 - 02/2004
4	Fas Ligand Protein (Fas Ligand)IBA 09/2006 - 01/2002
3	Sucrose (Saccharose)IBA 01/2020 - 01/2015
3	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2019 - 05/2006
3	Peptides (Polypeptides)IBA 10/2018 - 11/2005
3	MyokinesIBA 01/2018 - 01/2009
3	WD repeat containing planar cell polarity effectorIBA 02/2016 - 07/2010
3	CollagenIBA 01/2016 - 05/2006
3	Phosphotransferases (Kinase)IBA 12/2015 - 04/2004
3	Protein Isoforms (Isoforms)IBA 12/2014 - 06/2007
3	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 07/2013 - 01/2009
3	Mechanistic Target of Rapamycin Complex 1IBA 01/2013 - 03/2009
3	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2013 - 07/2002
3	Glycoproteins (Glycoprotein)IBA 10/2011 - 01/2009
3	salicylhydroxamic acid (SHAM)IBA 09/2010 - 05/2006
3	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 12/2008 - 04/2005
3	erucylphosphocholineIBA 05/2008 - 08/2005
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 09/2006 - 12/2003
2	Choline (Choline Chloride)IBA 01/2022 - 02/2012
2	ChemokinesIBA 01/2019 - 02/2012
2	LDL Receptors (LDL Receptor)IBA 01/2017 - 05/2011
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2016 - 09/2010
2	Caspase 3 (Caspase-3)IBA 12/2015 - 05/2003
2	human FSTL1 proteinIBA 09/2015 - 10/2012
2	AlbuminsIBA 03/2015 - 12/2003
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 07/2014 - 08/2002
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 02/2014 - 10/2005
2	ProstaglandinsIBA 02/2014 - 10/2005
2	H-cadherin (T-cadherin)IBA 08/2013 - 12/2010
2	AndrogensIBA 07/2013 - 07/2010
2	Androgen Receptors (Androgen Receptor)IBA 07/2013 - 07/2010

Therapy/Procedure

9	Therapeutics 07/2022 - 06/2006
3	Ligation 10/2019 - 06/2007